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Extremely high temperatures break intramolecular interactions and ________ an enzyme, resulting in a loss of its function.

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All amino acids enter the cellular respiration pathway at the citric acid cycle.

A) True
B) False

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Compare and contrast chemical energy and radiant energy. Into which broad category of energy (kinetic or potential) does each fit? What are two examples of each type of energy that relate to human physiology?

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Chemical energy is potential energy and ...

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The optimal pH range for most human enzymes is


A) 1-2.
B) 4-6.
C) 6-8.
D) 8-10.
E) 13-14.

F) A) and D)
G) All of the above

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The binding of ATP to phosphofructokinase inhibits the glycolytic pathway.

A) True
B) False

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Explain the relationship between activation energy and reaction rate. For example, how would an increase in activation energy affect reaction rate? How do biological systems differ from lab settings when considering these chemical variables?

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Higher activation energy requirements wo...

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The proteins in the electron transport chain transport H+


A) from the cytosol to the matrix.
B) from the matrix to the outer compartment.
C) from the outer compartment to the cytosol.
D) from the outer compartment to the matrix.
E) from the cristae to the matrix.

F) A) and E)
G) B) and E)

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During the citric acid cycle, an acetyl CoA molecule produced in the intermediate stage combines with a molecule of


A) oxaloacetic acid.
B) pyruvate.
C) citrate.
D) succinate.

E) A) and B)
F) B) and C)

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The first stage of cellular respiration is


A) electron transport, and it occurs in the cytosol.
B) electron transport, and it occurs in the mitochondria.
C) glycolysis, and it occurs in the cytosol.
D) glycolysis, and it occurs in the mitochondria.
E) the citric acid cycle, and it occurs at the mitochondria.

F) A) and C)
G) None of the above

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In the first step of the electron transport chain, the coenzymes NADH and FADH2 are oxidized.

A) True
B) False

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When multiple enzymes are organized in a metabolic pathway, each enzyme catalyzes one reaction and then releases the product.

A) True
B) False

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Enzyme saturation occurs when substrate levels are so high that all enzyme molecules are actively engaged in the chemical reaction, and so further increases in substrate concentration do not increase reaction rate.

A) True
B) False

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Hexokinase is an enzyme involved in cellular respiration and its substrate is glucose. Considering this information, hexokinase must be located


A) in the lumen of the stomach.
B) in the lumen of the small intestine.
C) inside the mitochondria of cells.
D) in the cytosol of cells.

E) A) and C)
F) A) and B)

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The optimal pH range for the stomach enzyme pepsin is


A) 2-4.
B) 6-8.
C) 7.3-7.4.
D) 10-12.
E) 12.0-13.5.

F) B) and E)
G) A) and E)

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The reaction in which water and carbon dioxide combine to form carbonic acid is


A) irreversible, as carbonic acid rapidly causes a drop in pH.
B) reversible, and can proceed in either direction depending on the concentrations of the molecules.
C) exergonic, and is an important energy source within the body.
D) an exchange reaction in which protons are transferred between atoms.
E) a catabolic reaction in which the formation of a larger molecule can lead to an increase in cell size.

F) B) and E)
G) B) and D)

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An enzyme that is described as a protein kinase is a(n)


A) hydrolase that removes an amino acid from a protein.
B) transferase that transfers a phosphate group to a protein substrate.
C) ligase that adds an amino acid to a protein.
D) isomerase that changes one protein into another.
E) protease that transfers electrons from one protein to another.

F) A) and C)
G) C) and E)

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Cofactors are generally proteins.

A) True
B) False

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In substrate-level phosphorylation, energy is first released to coenzymes and then transferred to form ATP.

A) True
B) False

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The enzyme that harnesses the energy of H+ diffusion down its concentration gradient within a mitochondrion to make high-energy molecules for the cell is


A) ATP phosphatase.
B) ATP synthase.
C) pyruvate decarboxylase.
D) succinic dehydrogenase.
E) creatine phosphatase.

F) B) and E)
G) None of the above

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Briefly describe how enzymes are named. What is generally used for the root of the name, and what is generally used as the suffix? Provide one example.

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The root is usually the substr...

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