Question 1

An example of natural active immunity would be _______.

Accepted Answer

A)   chickenpox vaccine triggering extended immunity to chickenpox
B)   chickenpox infection, followed by lifelong immunity
C)   giving a person immune serum globulins to chickenpox virus after exposure to the disease
D)   a fetus acquiring maternal IgG to the chickenpox virus across the placentaE) A) and B)
F) C) and D)

Question 2

Edward Jenner's work involved _______.

Accepted Answer

A)   immunization using a related, less pathogenic organism to give protection against a more pathogenic one
B)   development of passive immunotherapy
C)   development of an immunization to protect people against cowpox
D)   inoculation of dried pus from smallpox pustules into a person to stimulate immunityE) B) and C)
F) A) and B)

Question 3

Which of the statements below represents the correct order of events in the adaptive immune response?

Accepted Answer

A)   Lymphocyte development, antigen presentation, lymphocyte challenge, lymphocyte response
B)   Lymphocyte challenge, antigen presentation, lymphocyte development, lymphocyte response
C)   Antigen presentation, lymphocyte challenge, lymphocyte development, lymphocyte response
D)   Antigen presentation, lymphocyte development, lymphocyte challenge, lymphocyte responseE) A) and D)
F) None of the above

Question 4

A cytotoxic T lymphocyte, having been activated against a particular viral antigen, "sees" this same antigen displayed on the surface of a host cell. What will happen?

Accepted Answer

A)   The cytotoxic body cell will activate B cells which then produce antibody against the antigen.
B)   The cytotoxic T cell will produce antibodies against the antigen.
C)   The antigen will move inside of the host body cell, thereby hiding from the cytotoxic T cell.
D)   The cytotoxic T cell will produce proteins that cause the host body cell to die.E) None of the above
F) A) and D)

Question 5

The antibody-secreting progeny cells of a B-cell clone are called _______.

Accepted Answer

A)   antibodies
B)   bursa cells
C)   plasma cells
D)   sensitized T cells
E)   activated macrophagesF) All of the above
G) B) and D)

Question 6

The embryonic yolk sac, the liver, and the bone marrow are sites where _______.

Accepted Answer

A)   antigen is ﬁltered from tissue ﬂuid
B)   antigen is ﬁltered from the blood
C)   T lymphocytes complete maturation
D)   stem cells give rise to immature lymphocytes
E)   immune responses to antigen occurF) A) and E)
G) B) and E)

Question 7

The most signiﬁcant cells in graft rejection are _______.

Accepted Answer

A)   delayed hypersensitivity T cells
B)   natural killer (NK)  cells
C)   suppressor T cells
D)   helper T cells
E)   cytotoxic T cellsF) C) and D)
G) All of the above

Question 8

The hinge region of an antibody has a hypervariable amino acid region where the antigenic determinant ?ts.

Accepted Answer

A) True 
 B)False

Question 9

Which process involves antibodies cross-linking cells or particles into large aggregates?

Accepted Answer

A)   Opsonization
B)   Complement ﬁxation
C)   Agglutination
D)   Neutralization
E)   Anamnestic responseF) D) and E)
G) B) and E)

Question 10

B cell receptors differ from T cell receptors in that _______.

Accepted Answer

A)   B cell receptors are comprised of four polypeptides, whereas T cell receptors have only two polypeptides in their quaternary structure
B)   B cell receptors have two antigen binding sites, whereas T cell receptors have only one antigen binding site
C)   B cell receptors are immunoglobulin in nature, whereas T cell receptors are not immunoglobulin molecules
D)   B cell receptor immunoglobulins can be secreted as antibodies, whereas T cell receptors are never secreted
E)   All of the choices represent differences between B cell and T cell receptors.F) D) and E)
G) A) and E)

Question 11

Immunotherapy is the _______.

Accepted Answer

A)   use of antitoxins
B)   use of immune serum globulin
C)   conferring of passive immunity
D)   administering of preformed antibodies
E)   All of these choices are correct.F) A) and E)
G) D) and E)

Question 12

MHC molecules are found on all of the following cells except ______.

Accepted Answer

A)   red blood cells
B)   eosinophils
C)   leukocytes
D)   islet of Langerhans cells
E)   epithelial cellsF) All of the above
G) B) and E)

Question 13

High titers of speci?c antibodies are characteristic of _______.

Accepted Answer

A)   toxoids
B)   speci?c immune globulin (SIG) 
C)   gamma globulin
D)   attenuated vaccines
E)   immune serum globulin (ISG) F) None of the above
G) B) and D)

Question 14

The third line of defense against foreign invaders can be described as having _______ and ________.

Accepted Answer

A)   speciﬁcity; memory
B)   complexity; versatility
C)   diversity; barriers
D)   surveillance; complexityE) A) and B)
F) A) and C)

Question 15

The major histocompatibility complex is _______.

Accepted Answer

A)   a set of glycoproteins, called MHC antigens, found on all body cells
B)   a set of genes that code for MHC glycoproteins
C)   found on the third chromosome
D)   located in the thymus gland
E)   All of these choices are correct.F) A) and C)
G) A) and D)

Question 16

Not all phagocytic cells are antigen-presenting cells. B cells, macrophages, and dendritic cells differ from neutrophils in that they synthesize _______.

Accepted Answer

A)   MHC-II receptors
B)   interleukin-2
C)   MHC-I receptors
D)   CD8 receptors
E)   CD4 receptorsF) C) and E)
G) A) and D)

Question 17

Which of the following is not a property of B cells?

Accepted Answer

A)   There are low numbers circulating in the blood.
B)   They require antigen presented with MHC proteins.
C)   They mature in the bone marrow.
D)   They have receptors called immunoglobulins.
E)   They produce plasma cells and memory cells.F) A) and E)
G) A) and B)

Question 18

The ability of TC cells to initiate apoptosis in virally-infected cells and cancer cells is dependent on their ability to produce ________ and ________; proteins that punch holes in the target cell membrane.

Accepted Answer

A)   interleukin-1; interleukin-2
B)   perforin; granzyme
C)   interferon; interleukins
D)   antibodies; interferonsE) C) and D)
F) All of the above

Question 19

The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a/an _______.

Accepted Answer

A)   epitope
B)   antigen binding site
C)   variable region
D)   haptenE) A) and B)
F) All of the above

Question 20

Vaccinia virus is often used in the technique to make _______.

Accepted Answer

A)   antibodies to toxin
B)   an adjuvant
C)   gamma globulin
D)   a booster
E)   a "Trojan horse" recombinant vaccineF) B) and C)
G) D) and E)

Exam 15: Host Defenses Ii: Specific Immunity and Immunization

Edward Jenner's work involved _______.

Correct AnswerverifiedShow Answer

The major histocompatibility complex is _______.

Correct AnswerverifiedShow Answer

The third line of defense against foreign invaders can be described as having _______ and ________.

Correct AnswerverifiedShow Answer

The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a/an _______.

Correct AnswerverifiedShow Answer

The embryonic yolk sac, the liver, and the bone marrow are sites where _______.

Correct AnswerverifiedShow Answer

The antibody-secreting progeny cells of a B-cell clone are called _______.

Correct AnswerverifiedShow Answer

Which process involves antibodies cross-linking cells or particles into large aggregates?

Correct AnswerverifiedShow Answer

Which of the statements below represents the correct order of events in the adaptive immune response?

Correct AnswerverifiedShow Answer

A cytotoxic T lymphocyte, having been activated against a particular viral antigen, "sees" this same antigen displayed on the surface of a host cell. What will happen?

Correct AnswerverifiedShow Answer

Not all phagocytic cells are antigen-presenting cells. B cells, macrophages, and dendritic cells differ from neutrophils in that they synthesize _______.

Correct AnswerverifiedShow Answer

High titers of speci?c antibodies are characteristic of _______.

Correct AnswerverifiedShow Answer

Vaccinia virus is often used in the technique to make _______.

Correct AnswerverifiedShow Answer

The ability of TC cells to initiate apoptosis in virally-infected cells and cancer cells is dependent on their ability to produce ________ and ________; proteins that punch holes in the target cell membrane.

Correct AnswerverifiedShow Answer

Immunotherapy is the _______.

Correct AnswerverifiedShow Answer

MHC molecules are found on all of the following cells except ______.

Correct AnswerverifiedShow Answer

The hinge region of an antibody has a hypervariable amino acid region where the antigenic determinant ?ts.

Correct AnswerverifiedShow Answer

The most signiﬁcant cells in graft rejection are _______.

Correct AnswerverifiedShow Answer

An example of natural active immunity would be _______.

Correct AnswerverifiedShow Answer

Which of the following is not a property of B cells?

Correct AnswerverifiedShow Answer

B cell receptors differ from T cell receptors in that _______.

Correct AnswerverifiedShow Answer

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The third line of defense against foreign invaders can be described as having _ and __.

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The ability of TC cells to initiate apoptosis in virally-infected cells and cancer cells is dependent on their ability to produce and ; proteins that punch holes in the target cell membrane.

Correct Answer
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