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Which of the following is the best definition of epidemiology?


A) The science of tracking the occurrence and distribution of diseases
B) The relative number of deaths resulting from a particular disease
C) Identification of a specific disease through evaluation of signs and symptoms
D) The global search for emerging diseases

E) B) and C)
F) A) and D)

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A

A change in a tissue marked by cells that vary in size and shape and show increased mitotic figures would be called:


A) metaplasia.
B) atrophy.
C) dysplasia.
D) hypertrophy.

E) C) and D)
F) A) and D)

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If the data collected from the research process confirm that the new treatment has increased effectiveness and is safe, this is called:


A) the placebo effect.
B) evidence-based research.
C) blind research studies.
D) approval for immediate distribution.

E) A) and B)
F) C) and D)

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The term pathogenesis refers to:


A) the development of a disease or sequence of events related to tissue changes involved in the disease process.
B) the determination of the cause(s) involved in the development of a malignant neoplasm.
C) the specific signs and symptoms involved in the change from an acute disease to a chronic disease.
D) the changes in cells of affected tissue that result in necrosis.

E) All of the above
F) None of the above

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Why are the predisposing factors for a specific disease important to health professionals?


A) To predict the prognosis
B) To determine treatments
C) To develop preventive measures
D) To develop morbidity statistics

E) A) and B)
F) B) and C)

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Routine application of sun block to skin would be an example of:


A) an iatrogenic cause of cancer.
B) a preventive measure.
C) a precipitating factor.
D) a predisposing condition.

E) B) and D)
F) A) and B)

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B

Which of the following is considered a systemic sign of disease?


A) Swelling of the knee
B) Fever
C) Pain in the neck
D) Red rash on the face

E) B) and C)
F) A) and B)

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Etiology is defined as the study of the:


A) causes of a disease.
B) course of a disease.
C) expected complications of a disease.
D) manifestations of a disease.

E) None of the above
F) A) and B)

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Which term is used to describe a new and secondary or additional problem that arises after the original disease has been established?


A) Symptoms
B) Occurrence
C) Manifestations
D) Complication

E) C) and D)
F) A) and B)

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All of the following are part of the Seven Steps to Health EXCEPT:


A) follow cancer screening guidelines.
B) use sun block agents whenever exposed.
C) participate in strenuous exercise on a regular daily basis.
D) choose high fiber, lower fat foods.

E) B) and C)
F) A) and D)

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All of the following statements are correct about cell damage EXCEPT:


A) The initial stage of cell damage often causes an alteration in metabolic reactions.
B) If the factor causing the damage is removed quickly, the cell may be able to recover and return to its normal state.
C) If the noxious factor remains for an extended period of time, the damage becomes irreversible and the cell dies.
D) Initially, cell damage does not change cell metabolism, structure, or function.

E) B) and C)
F) A) and D)

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Which of the following can cause cell injury or death? 1) Hypoxia 2) Exposure to excessive cold 3) Excessive pressure on a tissue 4) Chemical toxins


A) 1, 2
B) 2, 4
C) 1, 3, 4
D) 1, 2, 3, 4

E) A) and D)
F) B) and C)

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A type of cellular adaptation in which there is a decrease in cell size is referred to as:


A) hypertrophy.
B) metaplasia.
C) anaplasia.
D) atrophy.

E) C) and D)
F) B) and D)

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Which of the following statements is TRUE?


A) Alteration of DNA does not change cell function.
B) Damaged cells may be able to repair themselves.
C) All types of cells die at the same rate.
D) Mild ischemia causes immediate cell death.

E) B) and C)
F) A) and C)

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Which of the following would be the most likely cause of an iatrogenic disease?


A) An inherited disorder
B) A combination of specific etiological factors
C) An unwanted effect of a prescribed drug
D) Prolonged exposure to toxic chemicals in the environment

E) A) and B)
F) All of the above

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The term homeostasis refers to:


A) the causative factors in a particular disease.
B) maintenance of a stable internal environment.
C) a condition that triggers an acute episode.
D) a collection of signs and symptoms.

E) A) and B)
F) A) and C)

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During the evaluation process for a new therapy's effectiveness and safety, a double blind study may be conducted during:


A) the first stage.
B) the second stage.
C) the third stage.
D) any of these stages.

E) A) and B)
F) A) and C)

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A collection of signs and symptoms, often affecting more than one organ or system, that usually occur together in response to a certain condition is referred to as a (an) :


A) acute disease.
B) multiorgan disorder.
C) syndrome.
D) manifestation.

E) B) and D)
F) B) and C)

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C

When a group of cells in the body dies, the change is called:


A) ischemia.
B) gangrene.
C) hypoxia.
D) necrosis.

E) A) and C)
F) B) and C)

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Caseation necrosis refers to an area where:


A) cell proteins have been denatured.
B) cell are liquefied by enzymes.
C) dead cells form a thick cheesy substance.
D) bacterial invasion has occurred.

E) B) and D)
F) A) and D)

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