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Ex vivo gene therapy has been used to treat which of the following diseases?


A) SCID
B) cardiovascular disease
C) Huntington disease
D) endocrine disorder
E) all of these

F) B) and D)
G) A) and E)

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All of the RNAs


A) can be found in the ribosomes.
B) are translated into proteins.
C) are transcribed from DNA.
D) function within the nucleus.
E) interact with amino acids.

F) None of the above
G) D) and E)

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Which of the following is not a desirable trait commonly genetically engineered into plant?


A) disease resistant
B) salt sensitive
C) improved yield
D) modified wood pulp
E) drought tolerant

F) B) and E)
G) A) and C)

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Place the following steps for the cloning of a gene in order: Place the following steps for the cloning of a gene in order: 1) DNA ligase seals foreign DNA into a plasmid. 2) A restriction enzyme is used to cleave DNA. 3) The bacterium makes a product. 4) Some of the bacterial cells take up a recombinant plasmid. 5) The plasmid replicates on its own.


A) 2,1,4,5,3
B) 1,2,3,4,5
C) 3,1,2,4,5
D) 5,1,4,3,2
E) 1,3,2,4,5

F) B) and D)
G) D) and E)

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A

Which structure contains the anticodon?


A) the mRNA
B) the large ribosomal subunit
C) the small ribosomal subunit
D) the tRNA
E) the rRNA

F) B) and C)
G) A) and D)

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Both DNA and RNA are


A) found in the cytosol.
B) transcribed.
C) translated.
D) found in the nucleus.
E) considered the genetic material of the cell.

F) C) and E)
G) B) and E)

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In what way are DNA and RNA similar?


A) Both contain C,A,and G.
B) Both contain deoxyribose.
C) Both contain U,C,and G.
D) Both are single stranded.
E) Both form a double helix.

F) C) and E)
G) A) and D)

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A

Which of the following statements about PCR is not true?


A) PCR stands for "polymerizing copies of RNA."
B) PCR can create millions of copies of a segment of DNA in a test tube.
C) PCR uses DNA polymerase.
D) The amount of DNA doubles with each replication cycle.
E) The target is repeatedly replicated.

F) A) and D)
G) A) and C)

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Which of the following occurs during initiation of translation?


A) The ribosome moves down one codon so that the A site is available to receive an incoming tRNA.
B) The mRNA binds to the smaller of the two ribosomal subunits.
C) The polypeptide lengthens one amino acid at a time.
D) The ribosome dissociates into its two subunits and falls off the mRNA.
E) One of the three stop codons is reached.

F) B) and C)
G) A) and E)

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How many stop codons are there in the genetic code?


A) one
B) two
C) three
D) four
E) five

F) D) and E)
G) None of the above

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Researchers found three genes on chromosome 22 in chimpanzees that,when compared to our human genes,have given us insight into our evolution.What were those three genes?


A) genes for speech development, hearing, and smell
B) genes for chest size, cranial size, and leg length
C) genes for taste, opposable thumbs, and bipedalism
D) genes for speech development, opposable thumbs, and leg length
E) genes for food preference, bipedalism, and cranial size

F) A) and D)
G) None of the above

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One of the disadvantages of PCR is that it requires large amounts of starting material.

A) True
B) False

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Which of the following is not true about transcription factors?


A) Transcription factors are DNA-binding proteins.
B) Transcription factors are considered external cell regulators.
C) There are many different types of transcription factors.
D) Specialization of cells is determined/influenced by which transcription factors are active in the cell.
E) Genes code for transcription factors.

F) None of the above
G) A) and D)

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When the sequence CGCAAUGCAAGGA is translated,the corresponding protein will be arginine-asparagine- alanine-arginine.

A) True
B) False

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How many codons are there for leucine?


A) two
B) three
C) four
D) five
E) six

F) C) and E)
G) A) and E)

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The sugar in DNA is deoxyribose while the sugar in RNA is ribose.

A) True
B) False

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Organisms that have had a foreign gene inserted into them are called analytical products.

A) True
B) False

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Which of the following is not involved in gene cloning?


A) host cell
B) vector
C) restriction enzyme
D) dyes attached to nucleotides
E) "sticky" ends

F) A) and D)
G) C) and D)

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Which of the following is not a type of small RNA?


A) snoRNAs
B) tRNA
C) snRNAs
D) miRNAs
E) siRNAs

F) B) and C)
G) A) and E)

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B

What enzyme is responsible for transcription (formation of mRNA) ?


A) helicase
B) DNA polymerase
C) RNA polymerase
D) ligase
E) protease

F) A) and B)
G) B) and C)

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